ABSTRACT
In the present study 122 ovarian teratomas, reported from the department of pathology, Kasturba Medical College, Mangalore, were predominantly (76%) seen in the age group below 40 years and the peak incidence was in the third decade (39%). Menstrual disturbances, pain abdomen, pregnancy and abdominal distension were the presenting symptoms. Histologically 113 (92.6%) were benign cystic teratomas showing mainly ectodermal tissue derivatives. Struma ovarii (4 cases) revealed colloid, both macro- and microscopically. Immature teratomas (2 cases) were solid and showed embroynal tissue elements. Teratomas with malignant transformations (3 cases) were grossly nodular and were squamous cell carcinomas.
Subject(s)
Adult , Age Factors , Female , Humans , India/epidemiology , Menstruation Disturbances/etiology , Ovarian Neoplasms/complications , Teratoma/complicationsSubject(s)
Animals , Lung/drug effects , Lung Diseases, Interstitial/chemically induced , Male , Rats , Rats, Wistar , Thioacetamide/toxicityABSTRACT
A 44-year-old man presented with generalised progressive lax skin of 14 years duration associated with dysphagia, joint pains and hoarseness of voice. Examination revealed "blood hound" like facies, lox skin with loss of elasticity, dilated tortuous superficial vessels over extremities and back. Systemic involvement noted were oesophageal and pharyngeal diverticuli, inguinal hernia and dermatochalasis. Skin biopsy using Verhoeff Van Gieson's stain was suggestive of cutis laxa.
ABSTRACT
Metaplastic changes are commonly found at widespread locations occurring in both reactive and neoplastic conditions. They can simulate tumors histologically. Squamous metaplasia is rarely seen in areas of fibrosis and inflammation secondary to hemorrhage in nodular goiters. If it is extensive with associated degenerative changes and present clinically in the form of a nodule, cytopathologist must take care to differentiate this from primary or metastatic squamous cell carcinoma or even anaplastic carcinoma.